Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566314 | 1.00 | CA12 (0.53) | CA12CA2CA14RECQLTDP1 | |
| SCHEMBL523837 | 0.92 | CA2 (0.59) | CA12CA2CA14RECQLTDP1 | |
| SCHEMBL23332545 | 0.90 | TDP1 (0.46) | CA12CA2CA14RECQLTDP1 | |
| SCHEMBL18838912 | 0.87 | CA12 (0.43) | CA12CA2CA14RECQLTDP1 | |
| SCHEMBL23518259 | 0.86 | CA2 (0.44) | CA12CA2CA14RECQLTDP1 | |
| SCHEMBL11658424 | 0.85 | KMT2A (0.41) | CA12CA2CA14RECQLMEN1 | |
| SCHEMBL11661626 | 0.85 | KMT2A (0.41) | CA12CA2CA14RECQLMEN1 | |
| SCHEMBL11661632 | 0.85 | KMT2A (0.41) | CA12CA2CA14RECQLMEN1 | |
| SCHEMBL11658432 | 0.85 | KMT2A (0.41) | CA12CA2CA14RECQLMEN1 | |
| SCHEMBL21602768 | 0.85 | TDP1 (0.44) | CA12CA2CA14RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710008-B2 | Compounds, compositions and use | UNIVERSITETET I OSLO (NO) | 2014-04-29 | — | — | US | disclosed |
| US-20120245094-A1 | COMPOUNDS, COMPOSITIONS AND USE | UNIVERSITETET I OLSO (NO) | 2012-09-27 | — | — | US | disclosed |
| WO-2010073009-A2 | COMPOUNDS, COMPOSITIONS AND USE | UNIVERSITETET I OSLO (NO) | 2010-07-01 | — | — | WO | disclosed |
| CN-1196686-C | Method for storing quaternary ammonium salt | TOKUYAMA CORP (JP) | 2005-04-13 | — | — | CN | disclosed |
| CN-1372554-A | Method for preserving quaternary ammonium salts | TOKUYAMA CORP (JP) | 2002-10-02 | — | — | CN | disclosed |
| US-4428889-A | PREPARING THIOPEPTIDES FROM PEPTIDES | BRISTOL-MYERS COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4169141-A | 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents | SHERING CORPORATION (US) | 1979-09-25 | — | — | US | disclosed |
| US-4093610-A | CYCLIC DODECAPEPTIDE, MULTISTAGE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245094-A1 | COMPOUNDS, COMPOSITIONS AND USE | VIP, C9, NGLY1 | CA12 103/4885CA2 559/4885CA14 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.