Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.66 |
| ▸ | REN | P00797 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | IL1RN | P18510 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 6/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468048 | 1.00 | ACE (0.66) | ACERENCTSLCTSSCTSK | |
| SCHEMBL8257450 | 1.00 | ACE (0.66) | ACERENCTSLCTSSCTSK | |
| SCHEMBL27893082 | 0.97 | ACE (0.64) | ACERENCTSLCTSSCTSK | |
| SCHEMBL30643016 | 0.96 | ACE (0.71) | ACERENCTSLCTSSCTSK | |
| SCHEMBL27902194 | 0.96 | ACE (0.71) | ACERENCTSLCTSSCTSK | |
| SCHEMBL27902195 | 0.96 | ACE (0.71) | ACERENCTSLCTSSCTSK | |
| SCHEMBL8252259 | 0.93 | REN (0.63) | ACERENCTSLCTSSCTSK | |
| SCHEMBL12706510 | 0.91 | ACE (0.64) | ACERENCTSLCTSSCTSK | |
| SCHEMBL30638855 | 0.90 | ACE (0.78) | ACERENCTSLCTSSCTSK | |
| SCHEMBL3825352 | 0.90 | ACE (0.78) | ACERENCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077155-A1 | A METHOD OF PRODUCING AN N-BLOCKED PEPTIDE | ACTION FOR DEVELOPMENT OF RESEARCH SP. Z.O.O. (PL) | 2010-07-08 | — | — | WO | disclosed |