SCHEMBL346822

SCHEMBL346822

C=C(C)C(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
KDM4E B2RXH2 3/20 0.56
ALDH1A1 P00352 3/20 0.56
KDM4C Q9H3R0 2/20 0.56
HSD17B10 Q99714 3/20 0.52
POLB P06746 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
AKR1C3 P42330 2/20 0.52
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
AKR1C2 P52895 1/20 0.52
AKR1C1 Q04828 1/20 0.52
MEN1 O00255 1/20 0.52
CYP2D6 P10635 1/20 0.52
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.52
RXFP1 Q9HBX9 1/20 0.49
CSNK2A1 P68400 1/20 0.47
HPGD P15428 1/20 0.47
EPHX2 P34913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381797 1.00 MAPT (0.56) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL11998343 0.90 TDP1 (0.51) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL22200962 0.89 TDP1 (0.57) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL344699 0.87 KMT2A (0.56) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL31280644 0.87 KMT2A (0.56) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL3632249 0.87 TDP1 (0.54) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL2345864 0.86 KMT2A (0.55) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL2345867 0.86 KMT2A (0.55) MAPTKDM4EALDH1A1HSD17B10POLB
SCHEMBL11800290 0.85 KDM4C (0.60) MAPTKDM4EALDH1A1KDM4CHSD17B10
SCHEMBL22200953 0.84 SMN1; SMN2 (0.55) MAPTKDM4CPOLBTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872245-B2 Antiseptic polymer and synthesis thereof TRIMPH IP PTY LIMITED (AU) 2024-01-16 US claimed
EP-3515986-B1 DENTAL SELF-ADHESIVE RESIN CEMENT BISCO INC (US) 2022-03-09 EP claimed
US-11219639-B2 Antiseptic polymer and synthesis thereof TRIMPH IP PTY LTD (AU) 2022-01-11 US claimed
WO-2019034597-A1 FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2019-02-21 WO claimed
US-20140148526-A1 DENTAL BONDING AGENT AND COATING AGENT NATIONAL TAIWAN UNIVERSITY (TW) 2014-05-29 US claimed
US-20140050674-A1 Method for Improving Penetration or Long Term Adhesion of Compositions to Dental Tissues and Compositions Usable in Said Method UNIVERSITY OF OULU (FI) 2014-02-20 US claimed
EP-2571479-A2 DENTAL COMPOSITIONS Levin, Leana (US) 2013-03-27 EP claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
WO-2012146832-A2 A METHOD FOR IMPROVING PENETRATION OR LONG TERM ADHESION OF COMPOSITIONS TO DENTAL TISSUES AND COMPOSITIONS USABLE IN SAID METHOD OULUN YLIOPISTO (FI) 2012-11-01 WO claimed
US-20110275035-A1 DENTAL COMPOSITIONS DENTSPLY INTERNATIONAL INC. (US) 2011-11-10 US claimed
EP-1221929-B1 METHOD FOR IMPROVING THE STAY-ON PROPERTIES OF COSMETIC COMPOSITIONS OREAL (FR) 2006-09-06 EP claimed
US-6730133-B1 ENZYME IMMOBILIZED IN A SOL-GEL MATRIX; 2-ELECTRON OXIDOREDUCTASES, 4-ELECTRON OXIDOREDUCTASES AND PEROXIDASES; HYDROGEN PEROXIDE; HEAT STABILITY L'OREAL S.A. (FR) 2004-05-04 US claimed
US-5733949-A Antimicrobial adhesive composition for dental uses KURARAY CO., LTD. (JP) 1998-03-31 US claimed
US-5670559-A TREATMENT OF TEETH WITH COMPOUNDS OF IRON, COPPER AND COBALT SUN MEDICAL CO., LTD. (JP) 1997-09-23 US claimed
EP-0627960-B1 COLLOIDAL AND CONCENTRATED SOLUTION OF MONOCRYSTAL-PARTICLES FROM METALLIC OXIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATIONS RHONE POULENC CHIMIE (FR) 1996-11-27 EP claimed
US-5556897-A METAL COMPOUND, ACRYLIC MONOMERS, TRIALKYLBORON SUN MEDICAL CO., LTD. (JP) 1996-09-17 US claimed
EP-0241295-B1 PHARMACEUTICAL COMPOSITION FOR USE IN DESENSITIZING HYPERSENSITIVE DENTIN Masuhara, Eiichi (JP) 1992-08-12 EP claimed
US-4911922-A Pharmaceutical composition for use in desensitizing hypersensitive dentin EIICHI MASUHARA (JP) 1990-03-27 US claimed
US-4781913-A Pharmaceutical composition for use in desensitizing hypersensitive dentin Masuhara, Eiichi (JP) 1988-11-01 US claimed
EP-0241295-A2 Pharmaceutical composition for use in desensitizing hypersensitive dentin Masuhara, Eiichi (JP) 1987-10-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140148526-A1 DENTAL BONDING AGENT AND COATING AGENT PHOSPHO1, PDAP1, ITGA4 MAPT 1027/4885KDM4E 1651/4885ALDH1A1 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.