Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086307 | 0.84 | SLC6A2 (0.55) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL3467519 | 0.84 | SLC6A2 (0.55) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL7086304 | 0.84 | SLC6A2 (0.55) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL7078601 | 0.80 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7078597 | 0.80 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14136275 | 0.77 | DRD2 (0.71) | SLC6A4DRD2CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL8245301 | 0.76 | TACR1 (0.52) | — | |
| SCHEMBL10773009 | 0.76 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7812301 | 0.73 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4131932 | 0.72 | FFAR1 (0.57) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077200-A1 | A COMPOSITION COMPRISING NOR-ADRENALINE AND A NET INHIBITOR FOR ADMINISTERING TO A BRAIN-DEAD, HEART-BEATING POTENTIAL ORGAN DONOR. | IGELÖSA TRANSPLANTATION SCIENCE AB (SE) | 2010-07-08 | — | — | WO | disclosed |