Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859446 | 0.96 | PTPN1 (0.56) | PTPN1SMN1; SMN2KDM4ELMNAMMP3 | |
| SCHEMBL3466490 | 0.90 | CYP17A1 (0.52) | MMP3MMP2MME | |
| SCHEMBL3467061 | 0.89 | SMN1; SMN2 (0.47) | PTPN1SMN1; SMN2KDM4ELMNAMMP3 | |
| SCHEMBL1861903 | 0.85 | GRIK1 (0.59) | MMP3MMP2GRIK1MME | |
| SCHEMBL1863843 | 0.85 | SMN1; SMN2 (0.50) | PTPN1SMN1; SMN2KDM4ELMNAMMP3 | |
| SCHEMBL4222929 | 0.83 | CYP2C9 (0.49) | PTPN1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL1859143 | 0.83 | GRIK1 (0.56) | SMN1; SMN2MMP3MMP2GRIK1MAPT | |
| SCHEMBL1860416 | 0.81 | GRIK1 (0.68) | SMN1; SMN2MMP3MMP2GRIK1MAPT | |
| SCHEMBL7077494 | 0.81 | MMP2 (0.69) | KDM4ELMNAMMP3MMP2HTT | |
| SCHEMBL7078108 | 0.81 | NPC1 (0.50) | PTPN1SMN1; SMN2KDM4ELMNAMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |