Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126096 | 0.82 | KDM4E (0.33) | KDM4EACHEMAPK1 | |
| SCHEMBL4420241 | 0.79 | KDM4E (0.30) | KDM4E | |
| SCHEMBL605116 | 0.74 | KDM4E (0.35) | KDM4E | |
| SCHEMBL603258 | 0.74 | HRH4 (0.50) | — | |
| SCHEMBL604152 | 0.70 | HRH4 (0.54) | — | |
| SCHEMBL602506 | 0.70 | HRH4 (0.52) | — | |
| SCHEMBL2802085 | 0.70 | HRH4 (0.37) | — | |
| SCHEMBL4126665 | 0.70 | HRH2 (0.31) | — | |
| SCHEMBL602111 | 0.69 | HRH4 (0.53) | — | |
| SCHEMBL606126 | 0.68 | HRH4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072829-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-07-01 | — | — | WO | disclosed |