SCHEMBL4420241

SCHEMBL4420241

Nc1nc(O)c2oc3c(c2n1)CCC3

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3468420 0.79 KDM4E (0.35) KDM4E
SCHEMBL4126096 0.76 KDM4E (0.33) KDM4E
SCHEMBL603258 0.68 HRH4 (0.50)
SCHEMBL605116 0.68 KDM4E (0.35) KDM4E
SCHEMBL29404299 0.68 HRH4 (0.52)
SCHEMBL605096 0.68 HRH4 (0.52)
SCHEMBL603149 0.67 HRH4 (0.55)
SCHEMBL2802120 0.67 CYP1A2 (0.38) KDM4E
SCHEMBL13394086 0.66 KDM4E (0.53) KDM4E
SCHEMBL2802085 0.65 HRH4 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009056551-A1 FURO[3,2-D]PYRIMIDINE DERIVATIVES PALAU PHARMA, S. A. (ES) 2009-05-07 WO disclosed