SCHEMBL346868

SCHEMBL346868

OCCCNCCN=Cc1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.65
CA2 P00918 7/20 0.65
CA9 Q16790 6/20 0.65
KDM4E B2RXH2 5/20 0.64
CA1 P00915 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.42
GAA P10253 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CTRC Q99895 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN5 P54829 1/20 0.41
PTPN11 Q06124 1/20 0.41
GFER P55789 1/20 0.41
BACE1 P56817 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TRIM24 O15164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347721 0.95 CA12 (0.68) CA12CA2CA9KDM4ECA1
SCHEMBL347399 0.90 CA12 (0.68) CA12CA2CA9KDM4ECA1
SCHEMBL5350861 0.90 CA12 (0.78) CA12CA2CA9KDM4ECA1
SCHEMBL29610101 0.90 CA12 (0.78) CA12CA2CA9KDM4ECA1
SCHEMBL16221721 0.90 CA12 (0.78) CA12CA2CA9KDM4ECA1
SCHEMBL12996009 0.90 CA12 (0.78) CA12CA2CA9KDM4ECA1
SCHEMBL19209979 0.90 CA12 (0.78) CA12CA2CA9KDM4ECA1
SCHEMBL347803 0.89 CA12 (0.68) CA12CA2CA9KDM4ECA1
SCHEMBL6892005 0.89 CA12 (0.77) CA12CA2CA9KDM4ECA1
SCHEMBL14674400 0.89 CA12 (0.75) CA12CA2CA9KDM4ECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016033156-A1 IRON-CATALYZED OXIDATIVE POLYMERIZATION OF PHENOLS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-03 WO disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed
EP-1114836-B1 PROCESS FOR PRODUCING A RESIN COMPOSITION NAT INST OF ADVANCED IND SCIEN (JP) 2006-11-08 EP disclosed
US-6344516-B1 TRANSITION METAL COMPLEX CATALYST, OXIDATATIVE POLYMERIZATION OF PHENOL-CONTAINING VEGETABLE OIL NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-02-05 US disclosed
EP-1114836-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2001-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR CA12 1989/4885CA2 1431/4885CA9 1596/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR CA12 1977/4885CA2 1450/4885CA9 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.