SCHEMBL346874

SCHEMBL346874

O=C(O)C1=NC(C(=O)O)CC=C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13176921 0.84
SCHEMBL10203518 0.79
SCHEMBL24618741 0.78
SCHEMBL17281365 0.78
SCHEMBL13822798 0.69 HTR2B (0.32)
SCHEMBL19013071 0.68 HTR2A (0.32)
SCHEMBL24226137 0.68 KDM4E (0.43) TDP1
SCHEMBL10203521 0.67 ALDH1A1 (0.35)
SCHEMBL16850625 0.64
SCHEMBL7853600 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 985 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120022317-A Lucid ganoderma fermented green tea and preparation method and application thereof 湖南农业大学 2025-05-23 CN claimed
EP-4092040-B1 MICROORGANISM THAT PRODUCES LYSINE AND METHOD FOR PRODUCING LYSINE TIANJIN INST IND BIOTECHNOLOGY CAS (CN) 2025-03-05 EP claimed
EP-3153586-B1 METHOD FOR PRODUCING L-AMINO ACIDS AJINOMOTO KK (JP) 2023-05-10 EP claimed
CN-111607608-B Gene engineering high-yield strain streptomyces diastatochromogenes, method for improving yield of epsilon-polylysine and application 天津科技大学 2023-04-14 CN claimed
US-20220112471-A1 NADH-DEPENDENT AMINO ACID DEHYDROGENASE AND APPLICATION THEREOF IN INCREASING LYSINE YIELD TSINGHUA UNIVERSITY (CN) 2022-04-14 US claimed
CN-113462583-A Corynebacterium glutamicum producing amino acid and method for producing amino acid using the same 中国科学院天津工业生物技术研究所 2021-10-01 CN claimed
US-10889843-B2 Corynebacterium sp. microorganisms having l-lysine-producing ability and l-lysine producing method using same CJ CHEILJEDANG CORPORATION (KR) 2021-01-12 US claimed
CN-111607608-A Gene engineering high-yield strain streptomyces diastatochromogenes, method for improving yield of polylysine and application 天津科技大学 2020-09-01 CN claimed
CN-109182283-A The amino acid dehydrogenase of NADH dependence and its application in raising lysine production 清华大学 2019-01-11 CN claimed
EP-2851421-B1 USEFUL MICROORGANISM, AND METHOD FOR PRODUCING SUBSTANCE OF INTEREST KAO CORP (JP) 2018-11-28 EP claimed
WO-2005059093-A2 P EF-TU EXPRESSION UNITS BASF AKTIENGESELLSCHAFT (DE) 2005-06-30 WO claimed
CN-1094926-C Antimer pure acetacetates, its preparation method and use BAYER AG (DE) 2002-11-27 CN claimed
CN-1346402-A L-amino acid-producing bacterium and method for producing L-amino acid AJINOMOTO KK (JP) 2002-04-24 CN claimed
CN-1269359-A Antimer pure acetacetates, its preparation method and use BAYER AG (DE) 2000-10-11 CN claimed
JP-H09511124-A 1997-11-11 JP claimed
CN-1142856-A Method for producing L-lysine by fermentation AJINOMOTO KK (JP) 1997-02-12 CN claimed
EP-0734445-A1 CHIMERIC GEENS AND METHODS FOR INCREASING THE LYSINE CONTENT OF THE SEEDS OF CORN, SOYBEAN AND RAPESEED PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-02 EP claimed
US-5554522-A Dihydrodipicolinate reductase crystals and three dimensional structure ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) 1996-09-10 US claimed
WO-1995015392-A1 CHIMERIC GEENS AND METHODS FOR INCREASING THE LYSINE CONTENT OF THE SEEDS OF CORN, SOYBEAN AND RAPESEED PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-08 WO claimed
EP-0608722-A1 Biological screens for detection of herbicides AMERICAN CYANAMID COMPANY (US) 1994-08-03 EP claimed