Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | WRN | Q14191 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467489 | 0.88 | MEN1 (0.76) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467876 | 0.82 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11875081 | 0.81 | BLM (0.80) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3467505 | 0.81 | KMT2A (0.51) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5439968 | 0.80 | MEN1 (0.73) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8561964 | 0.79 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8559872 | 0.78 | HTT (0.73) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5439628 | 0.78 | MEN1 (0.55) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5441202 | 0.78 | MEN1 (0.57) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5441682 | 0.78 | MEN1 (0.66) | HTTSMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |