Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dipentylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | ADH7 | P40394 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipentylamine SCHEMBL7568173 | 0.98 | ALDH1A1 (0.62) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL28881947 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL28881953 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL28881967 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL7562827 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL7567094 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL6390465 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL7562435 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL6392617 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Nitric Acid SCHEMBL28881965 | 0.95 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180169062-A1 | Palladium Lipoic Acid Complex Formulation As An Adjunct In Radiotherapy | Garnett McKeen Laboratory | 2018-06-21 | — | — | US | disclosed |
| WO-2016191559-A1 | PALLADIUM LIPOIC ACID COMPLEX FORMULATION AS AN ADJUNCT IN RADIOTHERAPY | GARNETT MCKEEN LABORATORY, INC. (US) | 2016-12-01 | — | — | WO | disclosed |
| WO-2010111218-A1 | METHOD FOR INCREASING ENERGY IN HIV AND/OR AIDS PATIENTS | TYLER LUCY (US) | 2010-09-30 | — | — | WO | disclosed |