Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.46 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467556 | 0.84 | EED (0.51) | EEDTTKRAB9AKDM4ENPC1 | |
| SCHEMBL3469470 | 0.84 | EED (0.51) | EEDFYNTTKRAB9AKDM4E | |
| SCHEMBL3467195 | 0.83 | TTK (0.61) | FYNTTKADORA3ATP1A1ATP1B1 | |
| SCHEMBL3466394 | 0.81 | EED (0.51) | EEDTTK | |
| SCHEMBL3469554 | 0.79 | TTK (0.64) | TTKATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL12409314 | 0.79 | MAPK1 (0.50) | EEDFYNTTKRAB9AKDM4E | |
| SCHEMBL3469327 | 0.79 | EED (0.48) | EEDFYNTTKRAB9AADORA3 | |
| SCHEMBL3469812 | 0.78 | ZAP70 (0.47) | EEDFYNRAB9AKDM4ENPC1 | |
| SCHEMBL3469473 | 0.78 | EED (0.49) | EEDFYNTTKADORA3KDM4E | |
| SCHEMBL5403304 | 0.78 | FLT3 (0.50) | TTKATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |