Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470290 | 0.89 | GAA (0.46) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20519927 | 0.88 | L3MBTL1 (0.57) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL3469737 | 0.85 | HDAC3 (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL10904330 | 0.82 | CYP2C9 (0.41) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL10898812 | 0.81 | GAA (0.40) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL10902735 | 0.80 | GAA (0.40) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20520156 | 0.80 | HDAC3 (0.48) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20520099 | 0.80 | HDAC3 (0.48) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL20519926 | 0.80 | HDAC3 (0.48) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL10903227 | 0.80 | SPHK1 (0.40) | GAAXBP1ATMNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |