Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17571398 | 0.89 | PDE4D (0.48) | PDE4APDE4D | |
| SCHEMBL508221 | 0.89 | PDE4D (0.59) | PDE4APDE4D | |
| SCHEMBL10165149 | 0.86 | PDE4A (0.48) | PDE4APDE4D | |
| SCHEMBL509637 | 0.84 | PDE4D (0.59) | PDE4APDE4D | |
| SCHEMBL509400 | 0.83 | PDE4A (0.61) | PDE4APDE4D | |
| SCHEMBL509401 | 0.81 | PDE4A (0.64) | PDE4APDE4D | |
| SCHEMBL3469602 | 0.79 | PDE4A (0.52) | PDE4APDE4D | |
| SCHEMBL3469404 | 0.79 | PDE4D (0.47) | PDE4APDE4D | |
| SCHEMBL510059 | 0.78 | PDE4A (0.59) | PDE4APDE4D | |
| SCHEMBL508899 | 0.77 | PDE4D (0.67) | PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379548-B1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | LEO PHARMA AS (DK) | 2016-03-09 | — | — | EP | disclosed |
| US-8952162-B2 | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases | LEO PHARMA A/S (DK) | 2015-02-10 | — | — | US | disclosed |
| WO-2010069322-A1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | LEO PHARMA A/S (DK) | 2010-06-24 | — | — | WO | disclosed |