SCHEMBL3466151

SCHEMBL3466151

CC(C)CNc1nccn2c(-c3cccc(O)c3)cnc12

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTK P33981 19/20 0.62
FLT3 P36888 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3467927 0.86 TTK (0.74) TTKFLT3
SCHEMBL3470178 0.85 TTK (0.67) TTK
SCHEMBL5420238 0.83 FLT3 (0.52) TTKFLT3
SCHEMBL3470453 0.83 TTK (0.64) TTK
SCHEMBL3466464 0.83 TTK (0.48) TTKFLT3
SCHEMBL12409229 0.81 TTK (0.51) TTK
SCHEMBL3469144 0.81 TTK (0.61) TTK
SCHEMBL12409318 0.80 ADORA3 (0.52) TTK
SCHEMBL3471112 0.80 FYN (0.47) TTK
SCHEMBL3469482 0.80 TTK (0.71) TTKFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO claimed
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO disclosed