Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16367301 | 0.84 | CHRM1 (0.42) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL16367384 | 0.83 | MAPK1 (0.40) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL27991993 | 0.83 | CHRM1 (0.40) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL16367324 | 0.81 | CHRM1 (0.39) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL16367323 | 0.81 | CHRM1 (0.39) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL16367322 | 0.81 | MAPK1 (0.38) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL15607866 | 0.81 | MAPK1 (0.38) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL16367351 | 0.81 | MAPK1 (0.38) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL27895123 | 0.81 | CHRM1 (0.55) | MAPK1ATMCHRM1LMNAALDH1A1 | |
| SCHEMBL11618755 | 0.78 | ALDH1A1 (0.43) | MAPK1ATMCHRM1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541727-B | A kind of lipid molecular, its preparation method and its application in tumour radiotherapy medicine for having radio therapy sensitization function | 徐州医学院 | 2018-01-30 | — | — | CN | claimed |
| CN-105541727-A | Lipid molecule with radiotherapy sensitization, preparation method of lipid molecule and application of lipid molecule in tumor radiotherapy drugs | XUZHOU MEDICAL COLLEGE | 2016-05-04 | — | — | CN | claimed |
| CN-105541727-A | Lipid molecule with radiotherapy sensitization, preparation method of lipid molecule and application of lipid molecule in tumor radiotherapy drugs | XUZHOU MEDICAL COLLEGE | 2016-05-04 | — | — | CN | disclosed |
| CN-103772289-B | The method of synthesis secnidazole and secnidazole | HUNAN DINUO PHARMACEUTICAL CO., LTD. (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-103772289-A | Method for synthesizing secnidazole and secnidazole | HUNAN DINUO PHARMACEUTICAL CO LTD | 2014-05-07 | — | — | CN | disclosed |
| EP-2238980-A1 | Aqueous compositions containing metronidazole | Dow Pharmaceutical Sciences (US) | 2010-10-13 | — | — | EP | disclosed |