Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275206 | 0.94 | MAPK8 (0.54) | ADORA3MAPK8FLT3HCRTR2KDM4E | |
| SCHEMBL5398296 | 0.93 | ADORA3 (0.53) | ADORA3MAPK8FLT3HCRTR2 | |
| SCHEMBL8246210 | 0.77 | AURKA (0.55) | ADORA3MAPK8FLT3 | |
| SCHEMBL14529893 | 0.76 | ADORA3 (0.48) | ADORA3MAPK8FLT3 | |
| SCHEMBL19068534 | 0.75 | HCRTR2 (0.43) | ADORA3HCRTR2ADORA1 | |
| SCHEMBL11940635 | 0.74 | ADORA3 (0.56) | ADORA3 | |
| SCHEMBL14537078 | 0.74 | ADORA3 (0.46) | ADORA3MAPK8FLT3 | |
| SCHEMBL16041123 | 0.74 | HCRTR2 (0.42) | ADORA3FLT3HCRTR2ADORA1 | |
| SCHEMBL2269579 | 0.73 | FLT3 (0.55) | ADORA3FLT3HCRTR2 | |
| SCHEMBL19125214 | 0.73 | ADORA3 (1.00) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |