Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.60 |
| ▸ | RAD52 | P43351 | 13/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477971 | 0.90 | TTK (0.64) | TTKFYN | |
| SCHEMBL3469452 | 0.83 | TTK (0.64) | TTKFYN | |
| SCHEMBL3469961 | 0.83 | CAMK2D (0.54) | RAD52CAMK2DPAX8FYN | |
| SCHEMBL3469410 | 0.79 | RAD52 (0.62) | RAD52CAMK2DPAX8FYN | |
| SCHEMBL3469144 | 0.78 | TTK (0.61) | TTKFYN | |
| SCHEMBL3469619 | 0.78 | TTK (0.59) | TTKFYN | |
| SCHEMBL2258603 | 0.78 | FYN (0.75) | CAMK2DIKBKBFYN | |
| SCHEMBL11939385 | 0.77 | TTK (0.51) | TTKCAMK2DFYN | |
| SCHEMBL15375701 | 0.76 | TTK (1.00) | TTK | |
| SCHEMBL3469392 | 0.76 | FYN (0.56) | TTKPAX8FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |