Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 8/20 | 0.53 |
| ▸ | BRAF | P15056 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467717 | 0.80 | FYN (0.45) | FYNRIPK2FGFR3KDRDYRK3 | |
| SCHEMBL3469970 | 0.79 | BRAF (0.57) | FYNBRAFKMT2AMEN1NPC1 | |
| SCHEMBL3469617 | 0.79 | FYN (0.48) | FYNRIPK2FGFR3KDRDYRK3 | |
| SCHEMBL5416134 | 0.73 | FYN (0.54) | FYNBRAFRIPK2DYRK3CCNT1 | |
| SCHEMBL3466056 | 0.72 | TTK (0.57) | FYNBRAFNPC1RIPK2DYRK3 | |
| SCHEMBL5401463 | 0.71 | TTK (0.52) | FYNFGFR3KDR | |
| SCHEMBL3469619 | 0.71 | TTK (0.59) | FYNFGFR3KDR | |
| SCHEMBL3466122 | 0.71 | TTK (0.55) | FYNBRAFDYRK3CCNT1CCNA2 | |
| SCHEMBL913697 | 0.69 | BRAF (0.46) | FYNBRAFKMT2A | |
| SCHEMBL3466505 | 0.69 | FYN (0.58) | FYNBRAFFGFR3KDRDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |