Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.57 |
| ▸ | FYN | P06241 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409300 | 0.87 | TUBB4A (0.46) | BRAFFYNKDM4EALDH1A1GAA | |
| SCHEMBL14767510 | 0.85 | ALDH1A1 (0.52) | FYNKDM4EALDH1A1GAAMAPT | |
| SCHEMBL3466304 | 0.85 | PDE5A (0.53) | FYNKDM4EALDH1A1GAAMAPT | |
| SCHEMBL3469850 | 0.84 | CLK4 (0.51) | FYNKDM4EALDH1A1GAAMAPT | |
| SCHEMBL12409290 | 0.82 | TTK (0.46) | BRAFFYNTTK | |
| SCHEMBL3471655 | 0.81 | FYN (0.59) | FYNKDM4EALDH1A1GAAMAPT | |
| SCHEMBL12409301 | 0.81 | PDE5A (0.52) | FYNKDM4EALDH1A1GAAMAPT | |
| SCHEMBL3467720 | 0.80 | FYN (0.62) | BRAFFYNKDM4EALDH1A1GAA | |
| SCHEMBL3466505 | 0.80 | FYN (0.58) | BRAFFYNTTKKDR | |
| SCHEMBL3469969 | 0.79 | FYN (0.53) | BRAFFYNKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |