SCHEMBL3470972

SCHEMBL3470972

NC[C@@H](N)Cc1cccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.51
CTNNB1 P35222 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2D6 P10635 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
AKT1 P31749 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
CA2 P00918 1/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
ACP3 P15309 1/20 0.42
SLC6A4 P31645 2/20 0.41
SIGMAR1 Q99720 1/20 0.41
MTNR1A P48039 1/20 0.40
NR2E1 Q9Y466 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3441407 1.00 TACR1 (0.51) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
Hydrochloric Acid SCHEMBL3472368 0.98 TACR1 (0.50) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL1193153 0.83 CTNNB1 (0.50) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL3681421 0.82 CYP1A2 (0.52) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL31332121 0.81 EPHX1 (0.61) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL4665442 0.80 TACR1 (0.48) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL7402726 0.78 CTNNB1 (0.53) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL31054201 0.78 HTR2A (0.55) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL266931 0.78 HTR2A (0.55) TACR1CTNNB1CYP1A2CYP2C19CYP2C9
SCHEMBL31054151 0.78 HTR2A (0.55) TACR1CTNNB1CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7767388-B2 Method for monitoring the stereoselectivity and relative rate of organic chemical reactions NUTECH VENTURES (US) 2010-08-03 US disclosed
US-20060263895-A1 Method for monitoring the stereoselectivity and relative rate of organic chemical reactions NUTECH VENTURES 2006-11-23 US disclosed