Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193153 | 0.86 | CTNNB1 (0.50) | TACR1CTNNB1TDP1CYP1A2CYP2C19 | |
| SCHEMBL289201 | 0.81 | TDP1 (0.54) | TACR1CTNNB1TDP1CYP1A2SLC1A3 | |
| SCHEMBL5324786 | 0.81 | TDP1 (0.54) | TACR1CTNNB1TDP1CYP1A2SLC1A3 | |
| SCHEMBL3470972 | 0.80 | TACR1 (0.51) | TACR1CTNNB1TDP1CYP1A2CYP2C19 | |
| SCHEMBL3441407 | 0.80 | TACR1 (0.51) | TACR1CTNNB1TDP1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3472368 | 0.79 | TACR1 (0.50) | TACR1CTNNB1TDP1CYP1A2CYP2C19 | |
| SCHEMBL31054201 | 0.78 | HTR2A (0.55) | TACR1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7402726 | 0.78 | CTNNB1 (0.53) | TACR1CTNNB1TDP1CYP1A2CYP2C19 | |
| SCHEMBL31054151 | 0.78 | HTR2A (0.55) | TACR1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL266931 | 0.78 | HTR2A (0.55) | TACR1CTNNB1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287493-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS | BAYER SCHERING PHARMA AG (DE) | 2008-11-20 | — | — | US | claimed |
| WO-2008131972-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-GAMMA-AMINOALCOHOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-11-06 | — | — | WO | claimed |
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | claimed |
| US-20080287493-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS | BAYER SCHERING PHARMA AG (DE) | 2008-11-20 | — | — | US | disclosed |
| WO-2008131972-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-GAMMA-AMINOALCOHOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287493-A1 | ARYLMETHYLEN SUBSTITUTED N-ACYL-Y-AMINOALCOHOLS | FSHR, CYP19A1, GNRHR | TACR1 871/4885CTNNB1 4776/4885TDP1 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.