Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970686 | 0.78 | LTA4H (0.87) | LTA4HPTGS2HRH3MEN1KMT2A | |
| SCHEMBL5438744 | 0.78 | LTA4H (0.87) | LTA4HPTGS2HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14966884 | 0.77 | LTA4H (0.84) | LTA4HPTGS2HRH3MEN1KMT2A | |
| SCHEMBL7819691 | 0.77 | LTA4H (0.90) | LTA4HPTGS2HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3472541 | 0.72 | LTA4H (0.58) | LTA4HPTGS2HRH3MEN1KMT2A | |
| SCHEMBL28285426 | 0.71 | HRH3 (0.88) | LTA4HPTGS2HRH3MEN1KMT2A | |
| SCHEMBL7134872 | 0.70 | LTA4H (1.00) | LTA4HPTGS2HRH3 | |
| SCHEMBL27466778 | 0.70 | LTA4H (0.38) | LTA4HMEN1KMT2AMCHR1 | |
| SCHEMBL21004113 | 0.70 | HRH3 (0.84) | LTA4HPTGS2HRH3MEN1KMT2A | |
| SCHEMBL11093348 | 0.69 | HRH3 (1.00) | LTA4HPTGS2HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074587-A2 | 5-O-SUBSTITUTED 3-N-ARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |