SCHEMBL3471114

SCHEMBL3471114

CCCCCC(CC)C(CC(C)(c1ccc(O)cc1)c1ccc(O)cc1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
TRPV1 Q8NER1 1/20 0.37
HSD17B3 P37058 7/20 0.36
PRSS1 P07477 2/20 0.34
CTSG P08311 2/20 0.34
CTRB1 P17538 2/20 0.34
CMA1 P23946 2/20 0.34
CA2 P00918 1/20 0.34
MAPK1 P28482 1/20 0.34
KIF11 P52732 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881888 0.84 ESR1 (0.40) ESR1ESR2ALDH1A1CYP3A4TRPV1
SCHEMBL3470639 0.81 ESR1 (0.45) ESR1ESR2ALDH1A1CYP3A4TRPV1
SCHEMBL1176816 0.81 ESR1 (0.45) ESR1ESR2ALDH1A1CYP3A4TRPV1
SCHEMBL3120808 0.76 ESR1 (0.51) ESR1ESR2ALDH1A1CYP3A4CA2
SCHEMBL656271 0.74 ESR1 (0.49) ESR1ESR2ALDH1A1CYP3A4CA2
SCHEMBL3471119 0.73 MAPK1 (0.43) ESR1ESR2ALDH1A1CYP3A4CA2
SCHEMBL3131833 0.73 ESR1 (0.51) ESR1ESR2ALDH1A1CYP3A4CA2
SCHEMBL27643509 0.72 GPR84 (0.50) CA2MAPK1
SCHEMBL450317 0.70 GPR84 (0.53) CA2MAPK1
SCHEMBL571167 0.70 GPR84 (0.53) CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838602-B2 Weatherable, thermostable polymers having improved flow composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-11-23 US disclosed
US-7605221-B2 Aromatic polycarbonateester block or random copolymer and polysiloxane blend primarily containing isophthalic and terephthalic acids, resorcinol and dimethylsilanediol monomers; films are radiation transparent; improved ductility at lower temperatures; aircraft components SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US disclosed
EP-2032624-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 EP disclosed
WO-2008002757-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 WO disclosed
US-20070122627-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-05-31 US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 US disclosed
US-20050159577-A1 Weatherable, thermostable polymers having improved flow composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-07-21 US disclosed
US-6861482-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2005-03-01 US disclosed
US-20030207123-A1 Weatherable, thermostable polymers having improved flow composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-11-06 US disclosed