SCHEMBL3471267

SCHEMBL3471267

NC(CC[C@H](N)C(=O)O)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 5/20 0.55
SLC1A3 P43003 4/20 0.55
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
ALDH1A1 P00352 3/20 0.50
SLC1A2 P43004 3/20 0.50
LTA4H P09960 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
SLC15A1 P46059 1/20 0.50
IDO1 P14902 2/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5618771 1.00 SLC1A1 (0.55) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL28361329 1.00 SLC1A1 (0.55) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL7754254 0.93 SLC1A1 (0.52) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL10994023 0.93 SLC1A1 (0.52) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL676303 0.93 SLC1A1 (0.52) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL30466149 0.93 SLC1A1 (0.52) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL10591983 0.93 SLC1A1 (0.52) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL11317176 0.89 SLC1A1 (0.48) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL20013355 0.88 LTA4H (0.49) SLC1A1SLC1A3ALPIPKMPTGS1
SCHEMBL4161005 0.88 IDO1 (0.53) SLC1A1SLC1A3ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070212358-A1 Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment BAUSCH & LOMB INCORPORATED 2007-09-13 US claimed
US-20070196350-A1 Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment BAUSCH & LOMB INCORPORATED 2007-08-23 US claimed
EP-0709373-B1 PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU (JP) 2001-10-17 EP claimed
US-20240245720-A1 COMPOSITIONS COMPRISING EXTRACELLULAR VESICLES AND AN ACTIVE AGENT AND USES THEREOF UNIV RAMOT (IL) 2024-07-25 US disclosed
CN-116209453-A Method for minimizing adverse effects on cell, tissue, organ systems and organism biology mediated by external effects using bioadhesion and steric interactions of copolymers having at least two moieties 静水疗法有限责任公司 2023-06-02 CN disclosed
WO-2022249180-A1 COMPOSITIONS COMPRISING EXTRACELLULAR VESICLES AND AN ACTIVE AGENT AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-12-01 WO disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
EP-0245662-B1 P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0154343-B1 ADSORBENT Research Development Corporation of Japan (JP) 1991-06-19 EP disclosed
EP-0331988-A1 Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-13 EP disclosed
US-4857656-A Active esters used for production of esters or amides and process for producing esters or amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-08-15 US disclosed
US-4785021-A OPTICAL RESOLUTION RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1988-11-15 US disclosed
US-4747956-A CROSSLINKED POLYAMINO ACID RESEARCH DEVELOPMENT CORPORATION (JP) 1988-05-31 US disclosed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP disclosed
US-4694044-A Adsorbent RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1987-09-15 US disclosed
EP-0154343-A2 Adsorbent Research Development Corporation of Japan (JP) 1985-09-11 EP disclosed