SCHEMBL3471819

SCHEMBL3471819

CCNC1(CC)CC(=O)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP19A1 P11511 5/20 0.38
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12385121 0.80 TSHR (0.48) TSHRNPSR1LMNAKDM4ECYP2C19
SCHEMBL3706662 0.67 TSHR (0.58) TSHRNPSR1LMNAKDM4ECYP2C19
SCHEMBL570644 0.66 CYP19A1 (0.48) TSHRNPSR1LMNAKDM4ECYP2C19
Ethosuximide SCHEMBL118395 0.66 TSHR (1.00) TSHRNPSR1LMNAKDM4ECYP2C19
Ethosuximide SCHEMBL4654769 0.66 TSHR (1.00) TSHRNPSR1LMNAKDM4ECYP2C19
Ethosuximide SCHEMBL34212 0.66 TSHR (1.00) TSHRNPSR1LMNAKDM4ECYP2C19
Ethosuximide SCHEMBL20980115 0.66 TSHR (1.00) TSHRNPSR1LMNAKDM4ECYP2C19
SCHEMBL9263511 0.64 KDM4E (0.31) LMNAKDM4ECYP2C19
Ethosuximide SCHEMBL9074587 0.64 TSHR (0.95) TSHRNPSR1LMNAKDM4ECYP2C19
SCHEMBL12385126 0.64 TSHR (0.54) TSHRNPSR1LMNAKDM4ECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094739-B1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-19 EP disclosed
US-9023939-B2 Polyolefin compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-05 US disclosed
US-8981013-B2 Functionalized olefin polymers, compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2015-03-17 US disclosed
US-8653191-B2 Polyolefin compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-18 US disclosed
EP-2294102-B1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM AND METHODS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-21 EP disclosed
US-20130059989-A1 Polyolefin Compositions and Articles Prepared Therefrom, and Methods for Making the Same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-03-07 US disclosed
CN-101657476-B Functionalized olefin polymers, compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES INC 2013-02-20 CN disclosed
US-8288470-B2 Polyolefin compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
EP-2125918-B1 FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-27 EP disclosed
US-20100292403-A1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2010-11-18 US disclosed
US-20100143651-A1 FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2010-06-10 US disclosed
CN-101657476-A Functionalized olefin polymers, compositions and articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES INC US 2010-02-24 CN disclosed
US-20100029827-A1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC (US) 2010-02-04 US disclosed
WO-2010008371-A1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM AND METHODS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2010-01-21 WO disclosed
CN-101605825-A Polyolefin compositions and articles made therefrom and methods for making the same DOW GLOBAL TECHNOLOGIES INC (US) 2009-12-16 CN disclosed
EP-2125918-A2 FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME Dow Global Technologies Inc. (US) 2009-12-02 EP disclosed
EP-2094739-A1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME Dow Global Technologies Inc. (US) 2009-09-02 EP disclosed
WO-2008079784-A2 FUNCTIONALIZED OLEFIN POLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2008-07-03 WO disclosed
WO-2008080111-A1 POLYOLEFIN COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2008-07-03 WO disclosed