SCHEMBL3471955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14622649	0.93	NPC1 (0.45)	RXRANR1H2NR1H3MEN1NPC1
	SCHEMBL3474287	0.91	RXRA (0.51)	RXRANR1H2NR1H3MEN1NPC1
	SCHEMBL3472886	0.89	HDAC3 (0.52)	RXRANR1H2NR1H3RAB9ANR3C2
	SCHEMBL3474392	0.83	RXRA (0.57)	RXRANR1H2NR1H3NR3C2HDAC3
	SCHEMBL3471938	0.83	ORAI1 (0.60)	RXRANR1H2NR1H3NR3C2HDAC3
	SCHEMBL3472951	0.83	RXRA (0.56)	RXRANR1H2NR1H3NPC1RAB9A
	SCHEMBL3471324	0.83	MAPT (0.59)	RXRANR1H2NR1H3NR3C2HDAC3
	SCHEMBL3474043	0.83	RXRA (0.58)	RXRANR1H2NR1H3MEN1KMT2A
	SCHEMBL3471253	0.83	RXRA (0.50)	RXRANR1H2NR1H3NR3C2HDAC3
	SCHEMBL3473035	0.83	CNR1 (0.55)	RXRANR1H2NR1H3NR3C2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.