SCHEMBL3472057

SCHEMBL3472057

Nc1cccc(C(c2ccccc2)(c2cccc(N)c2)C(F)(F)F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
MAPK1 P28482 1/20 0.61
MAOA P21397 4/20 0.48
CYP3A4 P08684 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
MAOB P27338 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
MAPT P10636 2/20 0.39
CYP19A1 P11511 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 3/20 0.39
PBRM1 Q86U86 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN5 P54829 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398895 0.94 TSHR (0.55) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL1140694 0.81 KIF11 (0.46) TSHRMAPK1MAOACYP3A4MAOB
SCHEMBL8582903 0.80 TSHR (0.61) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL160204 0.80 TSHR (0.58) TSHRMAPK1ALDH1A1PTPN1PTPN5
SCHEMBL16395922 0.79 TSHR (0.65) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL28372148 0.77 TSHR (0.68) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL3867382 0.77 TSHR (0.68) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL31000868 0.77 TSHR (0.68) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL29799449 0.77 TSHR (0.68) TSHRMAPK1MAOACYP3A4CASP1
SCHEMBL29373758 0.77 TSHR (0.68) TSHRMAPK1MAOACYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP claimed
US-7745516-B2 Composition of polyimide and sterically-hindered hydrophobic epoxy E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-29 US claimed
US-20090111948-A1 Compositions comprising polyimide and hydrophobic epoxy and phenolic resins, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2009-04-30 US claimed
EP-2027184-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-25 EP claimed
EP-1943311-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I.Du pont de nemours and company (US) 2008-07-16 EP claimed
WO-2007146382-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-21 WO claimed
US-20070290379-A1 Hydrophobic compositions for electronic applications E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US claimed
WO-2007047384-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-26 WO claimed
US-20070083016-A1 Photosensitive polyimide compositions E. I. DUPONT DE NEMOURS AND COMPANY 2007-04-12 US claimed
US-20070083017-A1 Compositions comprising polyimide and hydrophobic epoxy, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2007-04-12 US claimed
WO-2024053564-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE 住友ベークライト株式会社 2024-03-14 WO disclosed
WO-2023190309-A1 SURFACE-MODIFIER RESIN COMPOSITION 住友ベークライト株式会社 2023-10-05 WO disclosed
WO-2023054381-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING ELECTRONIC DEVICE, ELECTRONIC DEVICE AND LIGHT DEVICE 住友ベークライト株式会社 2023-04-06 WO disclosed
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP disclosed
US-8233261-B2 Composite organic encapsulants CDA PROCESSING LIMITED LIABILITY COMPANY (US) 2012-07-31 US disclosed
WO-2007047384-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-26 WO disclosed
US-20070083016-A1 Photosensitive polyimide compositions E. I. DUPONT DE NEMOURS AND COMPANY 2007-04-12 US disclosed
US-20070083017-A1 Compositions comprising polyimide and hydrophobic epoxy, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2007-04-12 US disclosed
US-4978573-A Ultrathin polyimide polymer films and their preparation HOECHST CELANESE CORP. (US) 1990-12-18 US disclosed
US-4929405-A Ultrathin polyimide polymer flims and their preparation HOECHST CELANESE CORP. (US) 1990-05-29 US disclosed