⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18047814 | 0.82 | — | — | |
| SCHEMBL6757384 | 0.79 | — | — | |
| SCHEMBL10424725 | 0.77 | — | — | |
| SCHEMBL2137763 | 0.75 | TET2 (0.39) | — | |
| SCHEMBL23950 | 0.75 | — | — | |
| SCHEMBL19968403 | 0.74 | FDPS (0.33) | — | |
| SCHEMBL27507733 | 0.74 | TET2 (0.35) | — | |
| SCHEMBL27815437 | 0.74 | SLC7A5 (0.33) | — | |
| SCHEMBL4652781 | 0.73 | — | — | |
| Methacrylic Acid SCHEMBL14631234 | 0.73 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110540-A2 | ANTIMICROBIAL POLYMER COATINGS AND A METHOD PRODUCING THEM VIA CHEMICAL VAPOUR DEPOSITION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-19 | — | — | WO | claimed |
| US-20060228966-A1 | Chemical vapor deposition of antimicrobial polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-12 | — | — | US | claimed |
| EP-2844642-B1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD PHARMA INC (US) | 2019-11-13 | — | — | EP | disclosed |
| US-9834518-B2 | Compounds for inhibiting cell proliferation in EGFR-driven cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834571-B2 | Compounds for inhibiting cell proliferation in EGFR-driven cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160244469-A1 | Compounds for Inhibiting Cell Proliferation in EGFR-Driven Cancers | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-08-25 | — | — | US | disclosed |
| EP-2704572-B1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD PHARMA INC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-20150166591-A1 | METHODS AND COMPOSITIONS FOR RAF KINASE MEDIATED DISEASES | ARIAD PHARMACEUTICALS, INC. | 2015-06-18 | — | — | US | disclosed |
| EP-2844642-A1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD PHARMACEUTICALS, INC. (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2704572-A1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2013169401-A1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD PHARMACEUTICALS, INC. (US) | 2013-11-14 | — | — | WO | disclosed |
| US-20120316135-A1 | Compounds for Inhibiting Cell Proliferation in EGFR-Driven Cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2012151561-A1 | COMPOUNDS FOR INHIBITING CELL PROLIFERATION IN EGFR-DRIVEN CANCERS | ARIAD PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20100303877-A1 | Controlled Release Hydrogel Films | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-12-02 | — | — | US | disclosed |
| US-7563734-B2 | Chemical vapor deposition of antimicrobial polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-21 | — | — | US | disclosed |
| WO-2006110540-A2 | ANTIMICROBIAL POLYMER COATINGS AND A METHOD PRODUCING THEM VIA CHEMICAL VAPOUR DEPOSITION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060228966-A1 | Chemical vapor deposition of antimicrobial polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-12 | — | — | US | disclosed |