SCHEMBL3472759

SCHEMBL3472759

CCCNC(=O)c1c[nH]c(Oc2oc3cccc(OCCCNCc4cccnc4)c3c2C)c1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 18/20 0.58
NMT1 P30419 18/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3470416 0.90 NMT2 (0.64) NMT2NMT1
SCHEMBL6871619 0.78 NMT2 (0.61) NMT2NMT1
SCHEMBL6874419 0.78 NMT2 (0.75) NMT2NMT1
SCHEMBL3475905 0.75 NMT2 (0.79) NMT2NMT1
SCHEMBL7041979 0.75 NMT2 (0.81) NMT2NMT1
SCHEMBL3472011 0.75 NMT2 (0.83) NMT2NMT1
SCHEMBL3472871 0.74 NMT2 (1.00) NMT2NMT1
SCHEMBL6863882 0.74 NMT2 (0.76) NMT2NMT1
SCHEMBL3472573 0.74 NMT2 (0.75) NMT2NMT1
SCHEMBL6870666 0.74 NMT2 (0.80) NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010134939-A2 MAMMALIAN GENES INVOLVED IN INFECTION Zirus, Inc. (US) 2010-11-25 WO disclosed