Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TGM1 | P22735 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439711 | 0.86 | KMT2A (0.71) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL22397597 | 0.86 | KMT2A (0.70) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL16140981 | 0.85 | KMT2A (1.00) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL1134070 | 0.81 | CYP1A1 (0.60) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL9843748 | 0.81 | GAA (0.66) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1039601 | 0.81 | KMT2A (0.76) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL5271791 | 0.81 | KMT2A (0.76) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL7934465 | 0.79 | KMT2A (0.73) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL7445670 | 0.79 | KMT2A (0.73) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL5597893 | 0.79 | KMT2A (0.73) | KMT2AMEN1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114544785-B | Flurbiprofen and detection method of impurities thereof | 远大生命科学(鞍山)有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-114544785-A | Method for detecting flurbiprofen and impurities thereof | 远大生命科学(辽宁)有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-112827368-A | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-114544785-B | Flurbiprofen and detection method of impurities thereof | 远大生命科学(鞍山)有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117705995-A | Analysis method of flurbiprofen related substances | 浙江东亚药业股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117705852-A | Method for measuring ethyl 2- (4-bromo-3-fluorophenyl) acetate content by nuclear magnetic resonance fluorine spectrum | 南京药石科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-112827368-B | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-114544785-A | Method for detecting flurbiprofen and impurities thereof | 远大生命科学(辽宁)有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112827368-A | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-2940000-B1 | PROCESS FOR PREPARING METHYL ACETATE | DALIAN INST CHEMICAL PHYSICS CAS (CN) | 2017-10-18 | — | — | EP | disclosed |
| US-9440226-B2 | Method for preparing methyl acetate | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2016-09-13 | — | — | US | disclosed |
| WO-2000027853-A1 | HYDROBORONATION PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-05-18 | — | — | WO | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0638566-B1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO KK (JP) | 1999-01-07 | — | — | EP | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |
| US-5539112-A | 5-aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0638566-A1 | 5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0347227-B1 | Pesticidal compositions | DU PONT (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5135744-A | PALATABLE SOLID PESTICIDAL COMPOSITIONS OF ETHYLENE AND VINYL ACETATE COPOLYMER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0347227-A1 | Pesticidal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-20 | — | — | EP | disclosed |