Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MB | P02144 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | RARG | P13631 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909121 | 0.83 | CYP1A1 (0.67) | CYP1A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9843748 | 0.83 | GAA (0.66) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL27937384 | 0.82 | CYP1A1 (0.84) | CYP1A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27616186 | 0.81 | MAPT (0.59) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL13059829 | 0.81 | POLB (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL3472843 | 0.81 | KMT2A (0.73) | ALDH1A1MAPTMEN1KMT2AMAOA | |
| SCHEMBL4807819 | 0.81 | TRPV1 (0.47) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL8876305 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL715695 | 0.81 | POLB (0.73) | ALDH1A1MEN1KMT2AGAARECQL | |
| SCHEMBL2781923 | 0.80 | EPHX2 (0.61) | ALDH1A1MAPTMEN1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951001-B2 | Hepatoprotectant acetaminophen mutual prodrugs | ACORDA THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160326107-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | NEUROGESX, INC. | 2016-11-10 | — | — | US | disclosed |
| US-20110263545-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | ACORDA THERAPEUTICS, INC. | 2011-10-27 | — | — | US | disclosed |
| CN-102149412-A | Hepatoprotectant acetaminophen mutual prodrugs | NEUROGESX INC | 2011-08-10 | — | — | CN | disclosed |
| EP-2285419-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | Neurogesx, Inc. (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009143299-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | NEUROGESX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| US-7119207-B2 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC (US) | 2006-10-10 | — | — | US | disclosed |
| CN-1432011-A | Benzoamide piperidine compounds as substance P antagonists | PFIZER PROD INC (US) | 2003-07-23 | — | — | CN | disclosed |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | PFIZER INC. | 2003-05-08 | — | — | US | disclosed |
| EP-1272484-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001077100-A2 | BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2001-10-18 | — | — | WO | disclosed |
| EP-0410471-A2 | 2-alkyl-4-methoxy-5-aminophenol or salt thereof, or 2-alkyl-4-methoxy-5-substituted aminophenol or salt thereof, and dyeing composition for keratin fibers comprising the same | Kao Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326107-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | PTGS1, HPGD, PYGL | CYP1A1 230/4885ALDH1A1 142/4885MAPT 2608/4885 |
| US-20110263545-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | PTGS1, HPGD, PYGL | CYP1A1 230/4885ALDH1A1 142/4885MAPT 2608/4885 |
| US-20030087925-A1 | Benzoamide piperidine containing compounds and related compounds | TACR1, VIPR1, VIPR2 | CYP1A1 1603/4885ALDH1A1 732/4885MAPT 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.