Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 4/20 | 0.61 |
| ▸ | GBA1 | P04062 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547993 | 1.00 | EED (0.61) | EEDGBA1KMT2AHRH4HRH3 | |
| SCHEMBL1761058 | 1.00 | EED (0.61) | EEDGBA1KMT2AHRH4HRH3 | |
| Hydrochloric Acid SCHEMBL3914926 | 0.98 | EED (0.60) | EEDGBA1KMT2AHRH4HRH3 | |
| Hydrochloric Acid SCHEMBL7068731 | 0.96 | EED (0.58) | EEDGBA1KMT2AHRH4HRH3 | |
| SCHEMBL9598369 | 0.95 | GBA1 (0.59) | EEDGBA1KMT2AHRH4HRH3 | |
| Cyclooctanamine SCHEMBL4971880 | 0.89 | EED (0.52) | EEDGBA1KMT2AHRH4HRH3 | |
| SCHEMBL4892499 | 0.89 | GBA1 (0.78) | EEDGBA1HRH4HRH3POLB | |
| SCHEMBL892689 | 0.89 | GBA1 (0.78) | EEDGBA1HRH4HRH3POLB | |
| SCHEMBL4889591 | 0.89 | GBA1 (0.78) | EEDGBA1HRH4HRH3POLB | |
| SCHEMBL13576621 | 0.86 | EED (0.59) | EEDGBA1KMT2AHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069979-A1 | PYRAN DERIVATIVES AS CCR3 MODULATORS | NYCOMED GMBH (DE) | 2010-06-24 | — | — | WO | disclosed |
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |