SCHEMBL892689

SCHEMBL892689

c1ccc(CC2CCNC2)cc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.78
EED O75530 1/20 0.49
KDM1A O60341 1/20 0.47
MAOB P27338 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HRH4 Q9H3N8 3/20 0.46
HRH3 Q9Y5N1 3/20 0.46
POLB P06746 1/20 0.46
CCR3 P51677 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4892499 1.00 GBA1 (0.78) GBA1EEDKDM1AMAOBSLC6A2
SCHEMBL4889591 1.00 GBA1 (0.78) GBA1EEDKDM1AMAOBSLC6A2
SCHEMBL31524060 0.89 GBA1 (0.62) GBA1EEDKDM1AMAOBHRH4
SCHEMBL1761058 0.89 EED (0.61) GBA1EEDSLC6A2SLC6A4SLC6A3
SCHEMBL3473180 0.89 EED (0.61) GBA1EEDSLC6A2SLC6A4SLC6A3
SCHEMBL8547993 0.89 EED (0.61) GBA1EEDSLC6A2SLC6A4SLC6A3
SCHEMBL9828599 0.88 GBA1 (0.64) GBA1EEDSLC6A2SLC6A4SLC6A3
SCHEMBL87612 0.88 GBA1 (1.00) GBA1SLC6A4POLBCCR3
SCHEMBL9598369 0.87 GBA1 (0.59) GBA1EEDSLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL3914926 0.87 EED (0.60) GBA1EEDSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP claimed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN claimed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN claimed
WO-2024079351-A1 NOVEL PIPERAZINE-BASED SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2024-04-18 WO claimed
WO-2024023284-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2024-02-01 WO claimed
CN-109250403-A A kind of helix transporting device for bar heat treatment process 深圳达芬奇创新科技有限公司 2019-01-22 CN claimed
CN-102227261-A Hydrogenation of ester, ketone or aldehyde groups with ruthenium complexes having di-amine and phosphorous-nitrogen bidentate ligand FIRMENICH & CIE 2011-10-26 CN claimed
CN-102164673-A Hydrogenation of esters or carbonyl groups with phosphino-oxide based ruthenium complexes FIRMENICH & CIE 2011-08-24 CN claimed
CN-100408643-C Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2008-08-06 CN claimed
CN-1800273-A Use of compounds produced by fermentation of marine microorganisms for combating biofouling HONGKONG SCIENCE AND TECHNOLOG (HK) 2006-07-12 CN claimed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US disclosed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP disclosed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN disclosed
CN-119948015-A Novel sulfonamides and their use as neuroprotective and/or nerve repair agents 基因密码公司 2025-05-06 CN disclosed
EP-0561847-A1 PHOTOSENSITIVE POLYMERS AND PRINTING PLATES. LASTRA SPA (IT) 1993-09-29 EP disclosed
WO-1992010523-A1 PHOTOSENSITIVE POLYMERS AND PRINTING PLATES LASTRA S.P.A. (IT) 1992-06-25 WO disclosed
US-4487772-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO. LTD. (JP) 1984-12-11 US disclosed
US-4468402-A Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-08-28 US disclosed
US-4454130-A CARDIOTONIC, HYPOTENSIVE AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 GBA1 298/4885EED 4019/4885KDM1A 4070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.