SCHEMBL347366

SCHEMBL347366

COC(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 1/20 0.42
HMGCR P04035 1/20 0.42
CHRM1 P11229 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
CPT2 P23786 2/20 0.36
KDM4E B2RXH2 1/20 0.36
FFAR1 O14842 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACLY P53396 3/20 0.34
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3729146 0.93 CYP2D6 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL12189845 0.89 CYP2D6 (0.38) CYP2C19HIF1ACYP2D6TSHRALDH1A1
1,4-Butanediol SCHEMBL3743493 0.89 FFAR1 (0.38) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Propylene Glycol SCHEMBL3730785 0.85 TDP1 (0.39) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL3728469 0.85 TSHR (0.39) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Tetraethylene Glycol SCHEMBL3746474 0.84 MEN1 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
Triethylene Glycol SCHEMBL3731014 0.84 MEN1 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL3738552 0.81 CYP4F2 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL3736963 0.81 CYP4F2 (0.41) CYP2C19HIF1ACYP2D6TSHRALDH1A1
SCHEMBL2468613 0.78 TDP1 (0.42) TSHRALDH1A1CPT2FFAR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421358-B2 Polymer film, preparation method thereof, and polymer film laminate comprising the same LG CHEM, LTD. (KR) 2025-09-23 US claimed
WO-2024233640-A1 COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-14 WO claimed
US-20240366543-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA HEMOSHEAR THERAPEUTICS INC (US) 2024-11-07 US claimed
US-20240142475-A1 COMPOSITIONS AND METHODS FOR THE DETECTION OF TUBERCULOSIS WASHINGTON UNIVERSITY 2024-05-02 US claimed
US-20240115566-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR ST JUDE CHILDRENS RES HOSPITAL INC (US) 2024-04-11 US claimed
EP-4319746-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA Hemoshear Therapeutics, Inc. (US) 2024-02-14 EP claimed
EP-4262814-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR St. Jude Children's Research Hospital, Inc. (US) 2023-10-25 EP claimed
US-20230313241-A1 RECOMBINANT MICROORGANISM FOR PRODUCING POLY(3- HYDROXYBUTYRATE-CO-3-HYDROXYVALERATE) KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-10-05 US claimed
US-20230089009-A1 Polymer Film, Preparation Method Thereof, and Polymer Film Laminate Comprising the Same LG CHEM, LTD. (KR) 2023-03-23 US claimed
EP-4082783-A1 POLYMER FILM, PREPARATION METHOD THEREOF, AND POLYMER FILM LAMINATE COMPRISING SAME Lg Chem, Ltd. (KR) 2022-11-02 EP claimed
US-20140141482-A1 METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE INVISTA North America S.á r.l. (US) 2014-05-22 US claimed
WO-2013188546-A2 METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE INVISTA TECHNOLOGIES S.À.R.L. (CH) 2013-12-19 WO claimed
US-20130189753-A1 METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE INVISTA NORTH AMERICA S.A R.L. (US) 2013-07-25 US claimed
WO-2013082542-A2 METHODS FOR BIOSYNTHESIZING 1,3BUTADIENE INVISTA NORTH AMERICA S.A.R.L. (US) 2013-06-06 WO claimed
EP-2501826-A1 NUTRIGENETIC BIOMARKERS FOR OBESITY AND TYPE 2 DIABETES MAS-Metabolic Analytical Services Oy (FI) 2012-09-26 EP claimed
US-20120225047-A1 NUTRIGENETIC BIOMARKERS FOR OBESITY AND TYPE 2 DIABETES MAS-METABOLIC ANALYTICAL SERVICES OY (FI) 2012-09-06 US claimed
WO-2011058232-A1 NUTRIGENETIC BIOMARKERS FOR OBESITY AND TYPE 2 DIABETES MAS-METABOLIC ANALYTICAL SERVICES OY (FI) 2011-05-19 WO claimed
CN-1809368-B Compositions and methods for controlling insects TYRATECH INC 2011-02-09 CN claimed
CN-101897342-A Preparation of insecticide solution and application thereof BESTCHEM CO LTD GUIYANG 2010-12-01 CN claimed
US-4572740-A Citric acid esters as blowing and nucleating agents in the processing plastics BOEHRINGER INGELHEIM KG (DE) 1986-02-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366543-A1 METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA MMAB, OTC, ME2 CYP2C19 1899/4885HIF1A 2266/4885CYP2D6 1644/4885
US-20240115566-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR HMGCR, GCDH, ACADM CYP2C19 2550/4885HIF1A 2181/4885CYP2D6 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.