SCHEMBL3474301

SCHEMBL3474301

O=C(CC(C(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O)OCCOCCOC(=O)CC(C(=O)O)(N1C(=O)CCC1=O)S(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610721 0.96
Ethylene SCHEMBL15005585 0.93
SCHEMBL3474302 0.81
Di(Hydroxyethyl)Ether SCHEMBL3474303 0.81
SCHEMBL859389 0.79
SCHEMBL9008981 0.79
SCHEMBL8744936 0.79
SCHEMBL8741717 0.76
SCHEMBL166391 0.76
Ethylene Glycol SCHEMBL4563857 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221241-A1 CONSTRAINED HIV ENVELOPE-BASED IMMUNOGEN THAT SIMULTANEOUSLY PRESENTS RECEPTOR AND CORECEPTOR BINDING SITES UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) 2010-09-02 US disclosed
WO-2007005934-A2 CONSTRAINED HIV ENVELOPE-BASED IMMUNOGEN THAT SIMULTANEOUSLY PRESENTS RECEPTOR AND CORECEPTOR BINDING SITES UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) 2007-01-11 WO disclosed