SCHEMBL3474384

SCHEMBL3474384

COc1ccccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.55
CA2 P00918 6/20 0.55
CA12 O43570 4/20 0.51
CA9 Q16790 4/20 0.51
TRIM24 O15164 1/20 0.51
PKM P14618 1/20 0.50
BRD4 O60885 3/20 0.49
CREBBP Q92793 1/20 0.49
SLC22A12 Q96S37 1/20 0.48
CA4 P22748 1/20 0.47
PTPN2 P17706 2/20 0.47
PTPN1 P18031 2/20 0.47
PTPN5 P54829 2/20 0.47
HSPD1 P10809 1/20 0.47
HSPE1 P61604 1/20 0.47
BRD2 P25440 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1826690 0.87 CA1 (0.55) CA1CA2CA12CA9TRIM24
SCHEMBL12508715 0.86 CA1 (0.51) CA1CA2CA12CA9CA4
Hydrochloric Acid SCHEMBL1822130 0.85 CA1 (0.50) CA1CA2CA12CA9CA4
SCHEMBL1135639 0.85 MAPT (0.53) CA1CA2CA12CA9BRD4
SCHEMBL3475106 0.84 CA1 (0.54) CA1CA2CA12CA9CA4
SCHEMBL3474682 0.83 CA1 (0.53) CA1CA2CA12CA9CA4
SCHEMBL3425356 0.83 CA1 (0.53) CA1CA2CA12CA9SLC22A12
SCHEMBL3423045 0.83 CA1 (0.53) CA1CA2CA12CA9CA4
SCHEMBL1814769 0.83 CA1 (0.57) CA1CA2CA12CA9CA4
SCHEMBL2409586 0.82 LMNA (0.61) CA1CA2CA12CA9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-07 US disclosed
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-07 US disclosed
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-07 US disclosed
WO-2009140309-A2 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2009-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256092-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BCL6, BTD CA1 4452/4885CA2 1155/4885CA12 564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.