Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.69 |
| ▸ | SSTR5 | P35346 | 9/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476435 | 0.95 | FAAH (0.74) | FAAHSSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL13436762 | 0.89 | FAAH (0.60) | FAAHSSTR5HRH1KCNH2PIK3CA | |
| SCHEMBL3476092 | 0.88 | FAAH (0.59) | FAAHSSTR5HRH1KCNH2PIK3CA | |
| SCHEMBL3477055 | 0.88 | FAAH (0.62) | FAAHSSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3477431 | 0.82 | FAAH (0.70) | FAAHSSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3474864 | 0.82 | FAAH (0.67) | FAAHSSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3476698 | 0.81 | FAAH (1.00) | FAAHSSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3476876 | 0.81 | FAAH (0.77) | FAAHSSTR5PIK3CAHDAC6 | |
| SCHEMBL3477435 | 0.80 | FAAH (0.75) | FAAHSSTR5HRH1PIK3CAHDAC6 | |
| SCHEMBL13436720 | 0.80 | FAAH (0.78) | FAAHSSTR5HRH1HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |