Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000805 | 0.93 | HPGD (0.62) | HPGDNPSR1MEN1KMT2AGAA | |
| SCHEMBL1001947 | 0.88 | BCHE (0.63) | GAABCHEACHENOX1 | |
| SCHEMBL3472676 | 0.84 | BCHE (0.58) | MEN1KMT2ABCHEACHE | |
| SCHEMBL24439579 | 0.79 | NOX1 (0.67) | HPGDNPSR1MEN1KMT2AGAA | |
| SCHEMBL1000540 | 0.79 | BCHE (0.65) | MEN1KMT2ABCHELMNAACHE | |
| SCHEMBL28624938 | 0.77 | BCHE (0.69) | HPGDNPSR1BCHEACHE | |
| SCHEMBL4858540 | 0.76 | NOX1 (0.50) | BCHEACHENOX1 | |
| SCHEMBL4556567 | 0.75 | BCHE (0.59) | NPSR1BCHEACHENOX1 | |
| SCHEMBL11781829 | 0.75 | HPGD (0.57) | HPGDNPSR1MEN1KMT2AGAA | |
| SCHEMBL25800339 | 0.74 | NOX1 (0.63) | HPGDNPSR1GAABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763760-B2 | Catalyst composition and method for halogenating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-07-27 | — | — | US | claimed |
| US-7557058-B2 | Catalyst composition and method for chlorinating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | claimed |
| JP-2008503461-A | — | — | 2008-02-07 | — | — | JP | claimed |
| US-7282615-B2 | Catalyst compositions and their use for chlorinating aromatic compounds | SABIC INNOVATIVE PLASTICS, IP BV | 2007-10-16 | — | — | US | claimed |
| EP-1778398-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060094912-A1 | toluene and o-xylene are chlorinated in the presence of a catalyst combination produced by (1) a combination of a salt of of 4-12 metal, lanthanide, actinides; and an organic acidic counterion; (2) an organic sulfur | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2006-05-04 | — | — | US | claimed |
| US-7012166-B2 | Catalyst composition and method for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY (US) | 2006-03-14 | — | — | US | claimed |
| WO-2006009661-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | claimed |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | claimed |
| US-20050283033-A1 | Catalyst compositions and their use for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | claimed |
| WO-2004082826-A2 | CATALYST COMPOSITION AND METHOD FOR CHLORINATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| US-20040186329-A1 | Catalyst composition and method for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-09-23 | — | — | US | claimed |
| US-7763760-B2 | Catalyst composition and method for halogenating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-07-27 | — | — | US | disclosed |
| US-7557058-B2 | Catalyst composition and method for chlorinating aromatic compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | disclosed |
| US-7282615-B2 | Catalyst compositions and their use for chlorinating aromatic compounds | SABIC INNOVATIVE PLASTICS, IP BV | 2007-10-16 | — | — | US | disclosed |
| EP-1778398-A2 | CATALYST COMPOSITION AND METHOD FOR HALOGENATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | disclosed |
| US-20050283033-A1 | Catalyst compositions and their use for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | disclosed |
| WO-2004082826-A2 | CATALYST COMPOSITION AND METHOD FOR CHLORINATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20040186329-A1 | Catalyst composition and method for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050283033-A1 | Catalyst compositions and their use for chlorinating aromatic compounds | PRKACG, PRKACA, PRKACB | HPGD 3785/4885NPSR1 3821/4885MEN1 2032/4885 |
| US-20040186329-A1 | Catalyst composition and method for chlorinating aromatic compounds | PRKACA, CLK4, PRKACG | HPGD 3379/4885NPSR1 2326/4885MEN1 3176/4885 |
| US-20060094912-A1 | toluene and o-xylene are chlorinated in the presence of a catalyst combination produced by (1) a combination of a salt of of 4-12 metal, lanthanide, actinides; and an organic acidic counterion; (2) an organic sulfur | CLIC4, CLK4, PRKACA | HPGD 2972/4885NPSR1 1530/4885MEN1 3617/4885 |
| US-20050283035-A1 | Catalyst compostion and method for halogenating aromatic compounds | AOC2, TYR, PRKX | HPGD 4091/4885NPSR1 2583/4885MEN1 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.