SCHEMBL3475178

SCHEMBL3475178

CC(C)(C)c1ccc(-c2ccccc2-c2ccccc2-c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.OPO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
CASP3 P42574 2/20 0.50
SENP8 Q96LD8 2/20 0.50
SENP7 Q9BQF6 2/20 0.50
SENP6 Q9GZR1 2/20 0.50
PLA2G1B P04054 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
TDP1 Q9NUW8 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080714 0.92 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL28326671 0.92 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL30932116 0.92 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL4969204 0.91 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL18063625 0.88 ALDH1A1 (0.42) ALDH1A1NPC1RAB9ACASP3SENP8
Phosphonic Acid SCHEMBL2197000 0.86 ALDH1A1 (0.51) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL7651048 0.86 ALDH1A1 (0.37) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL29763177 0.84 ALDH1A1 (0.48) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL2357462 0.84 ALDH1A1 (0.48) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL4920238 0.84 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921465-B2 Polybutylene terephthalate resin composition WINTECH POLYMER LTD. (JP) 2014-12-30 US disclosed
US-20130203905-A1 POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION WINTECH POLYMER LTD. (JP) 2013-08-08 US disclosed
EP-2578633-A1 POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION Wintech Polymer Ltd. (JP) 2013-04-10 EP disclosed
US-7643104-B2 Foamed resin sheet and liquid crystal display TEIJIN CHEMICALS, LTD. (JP) 2010-01-05 US disclosed
US-20090103003-A1 Foamed Resin Sheet and Liquid Crystal Display TEIJIN CHEMICALS LTD. (JP) 2009-04-23 US disclosed
US-20090021667-A1 Resin Sheet, Direct Backlight Unit, and Direct Backlight Type Liquid Crystal Display TEIJIN CHEMICALS LTD. (JP) 2009-01-22 US disclosed
EP-1302785-B1 PLASTIC LENS TEIJIN CHEMICALS LTD (JP) 2008-08-27 EP disclosed
EP-1870743-A1 RESIN SHEET, DIRECT BACKLIGHT UNIT, AND DIRECT BACKLIGHT TYPE LIQUID CRYSTAL DISPLAY Teijin Chemicals, Ltd. (JP) 2007-12-26 EP disclosed
US-20070104961-A1 Thermoplastic resin sheets provided with functionality by transfer method and their production processes NIPPON SHOKUBAI CO., LTD. (JP) 2007-05-10 US disclosed
US-6780965-B2 COPOLYCARBONATE RESIN BASED ON CYCLOHEXANEDIOL AND BISPHENOL COMPOUND; EXCELLENT IN FLOWABILITY, IT IS SUITABLE FOR EASILY MOLDING TEIJIN CHEMICALS LTD (JP) 2004-08-24 US disclosed
EP-1302785-A1 PLASTIC LENS Teijin Chemicals, Ltd. (JP) 2003-04-16 EP disclosed
US-20030055200-A1 Plastic lens TEIJIN CHEMICALS LTD. (JP) 2003-03-20 US disclosed