Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477243 | 0.86 | GRM2 (0.54) | GRM2TDO2 | |
| SCHEMBL13729571 | 0.85 | GRM2 (0.48) | GRM2TDO2 | |
| SCHEMBL3475341 | 0.84 | GRM2 (0.49) | GRM2TDO2 | |
| SCHEMBL3475089 | 0.81 | GRM2 (0.48) | GRM2TDO2 | |
| SCHEMBL3475865 | 0.80 | GRM2 (0.50) | GRM2 | |
| SCHEMBL13823858 | 0.80 | GRM2 (0.39) | GRM2 | |
| SCHEMBL3475495 | 0.80 | GRM2 (0.52) | GRM2TDO2 | |
| SCHEMBL3475381 | 0.79 | GRM2 (0.53) | GRM2TDO2 | |
| SCHEMBL3477224 | 0.79 | GRM2 (0.53) | GRM2TDO2 | |
| SCHEMBL13726878 | 0.78 | GRM2 (0.52) | GRM2TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141360-A1 | BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-12-09 | — | — | WO | claimed |
| WO-2010141360-A1 | BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141360-A1 | BIARYL BENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-12-09 | — | — | WO | disclosed |