Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389605 | 0.91 | MEN1 (0.69) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10389277 | 0.88 | SMN1; SMN2 (0.71) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL3476408 | 0.87 | SMN1; SMN2 (0.73) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10770076 | 0.87 | MEN1 (0.56) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL4314117 | 0.87 | MEN1 (0.56) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10767950 | 0.86 | MAPT (0.69) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10768749 | 0.86 | MEN1 (0.55) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10389884 | 0.84 | SMN1; SMN2 (0.64) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10694000 | 0.84 | SMN1; SMN2 (0.66) | MEN1RECQLKMT2APOLBSMN1; SMN2 | |
| SCHEMBL10389328 | 0.84 | SMN1; SMN2 (0.66) | MEN1RECQLKMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132286-A1 | ORALLY ADMINISTERED TABLET FORMULATION OF AN ANTIANXIOLYTIC COMPOUND | WYETH LLC (US) | 2010-11-18 | — | — | WO | claimed |
| WO-2010132286-A1 | ORALLY ADMINISTERED TABLET FORMULATION OF AN ANTIANXIOLYTIC COMPOUND | WYETH LLC (US) | 2010-11-18 | — | — | WO | disclosed |
| EP-1885367-A2 | METHOD FOR THE TREATMENT OF NOISE PHOBIA IN COMPANION ANIMALS | Wyeth (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006127574-A2 | METHOD FOR THE TREATMENT OF NOISE PHOBIA IN COMPANION ANIMALS | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0225272-A1 | 1-Methyl-15-alpha-alkyl-androsta-1,4-diene-3,17-diones, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-06-10 | — | — | EP | disclosed |
| EP-0223974-A1 | N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |