⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678890 | 0.73 | — | — | |
| SCHEMBL1160470 | 0.71 | — | — | |
| SCHEMBL1678566 | 0.69 | — | — | |
| SCHEMBL211577 | 0.67 | — | — | |
| SCHEMBL10446938 | 0.65 | FAAH (0.52) | — | |
| SCHEMBL11094414 | 0.65 | FAAH (0.52) | — | |
| SCHEMBL11317554 | 0.65 | — | — | |
| SCHEMBL14814511 | 0.65 | — | — | |
| SCHEMBL10436504 | 0.65 | FAAH (0.52) | — | |
| SCHEMBL8895259 | 0.65 | FAAH (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1715883-B1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER ANIMAL HEALTH GMBH (DE) | 2009-04-22 | — | — | EP | claimed |
| US-20080026990-A1 | 18-Membered Nitrobenzyl- and Aminobenzyl-Substituted Cyclohexadepsipeptides for Controlling Endoparasites and a Process for Their Preparation | BAYER HEALTHCARE AG (DE) | 2008-01-31 | — | — | US | claimed |
| JP-2007514671-A | — | — | 2007-06-07 | — | — | JP | claimed |
| EP-1715883-A1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | Bayer HealthCare AG (DE) | 2006-11-02 | — | — | EP | claimed |
| WO-2005063277-A1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER HEALTHCARE AG (DE) | 2005-07-14 | — | — | WO | claimed |
| US-7645738-B2 | 18-membered nitrobenzyl- and aminobenzyl-substituted cyclohexadepsipeptides for controlling endoparasites and a process for their preparation | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-12 | — | — | US | disclosed |
| EP-1715883-B1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER ANIMAL HEALTH GMBH (DE) | 2009-04-22 | — | — | EP | disclosed |
| US-20080026990-A1 | 18-Membered Nitrobenzyl- and Aminobenzyl-Substituted Cyclohexadepsipeptides for Controlling Endoparasites and a Process for Their Preparation | BAYER HEALTHCARE AG (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1715883-A1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | Bayer HealthCare AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005063277-A1 | 18-MEMBERED NITROBENZYL-SUBSTITUTED AND AMINOBENZYL-SUBSTITUTED CYCLOHEXADEPSIPEPTIDES FOR CONTROLLING ENDOPARASITES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER HEALTHCARE AG (DE) | 2005-07-14 | — | — | WO | disclosed |