Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370106 | 0.93 | HSD17B10 (0.32) | HSD17B10 | |
| SCHEMBL6254352 | 0.75 | — | — | |
| SCHEMBL1949104 | 0.72 | — | — | |
| SCHEMBL3483237 | 0.71 | — | — | |
| SCHEMBL17267279 | 0.70 | — | — | |
| SCHEMBL17668001 | 0.62 | MME (0.36) | HSD17B10TDP1ALDH1A1 | |
| SCHEMBL16047480 | 0.62 | HDAC1 (0.34) | ALDH1A1 | |
| SCHEMBL17818099 | 0.62 | — | — | |
| SCHEMBL6251832 | 0.62 | MME (0.31) | — | |
| SCHEMBL11822590 | 0.62 | TDP1 (0.48) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258724-A1 | Modulating immune responses using multimerized anti-CD83 antibodies | Celltech R & D, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| US-6670322-B2 | Covalently bonding a drug such as captopril to a biopolymeric delivery vehicle such as amino-dextrans, and conjugating the prodrug to a botulinum neurotoxin heavy chain; possible treatment for biological warfare exposure of the toxin | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-12-30 | — | — | US | disclosed |
| US-20030147921-A1 | Method of targeting pharmaceuticals to motor neurons | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-08-07 | — | — | US | disclosed |