SCHEMBL3476885

SCHEMBL3476885

Cn1ccc2cc(-c3ccc4oc(N5CCNCC5)nc4c3)ccc21

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.81
HTR6 P50406 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476620 0.90 FAAH (1.00) FAAH
SCHEMBL3476334 0.90 FAAH (0.95) FAAH
SCHEMBL3476187 0.88 FAAH (0.98) FAAH
SCHEMBL3477228 0.88 FAAH (0.84) FAAH
SCHEMBL3475629 0.88 FAAH (0.98) FAAH
SCHEMBL3477296 0.87 FAAH (1.00) FAAH
SCHEMBL3475423 0.85 FAAH (0.79) FAAH
SCHEMBL3475855 0.84 FAAH (0.78) FAAH
SCHEMBL3475427 0.84 FAAH (1.00) FAAH
SCHEMBL13436709 0.84 FAAH (0.78) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed