Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | APAF1 | O14727 | 3/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP4 | P49662 | 2/20 | 0.51 |
| ▸ | CASP5 | P51878 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773174 | 0.89 | KMT2A (0.49) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL2771524 | 0.88 | KMT2A (0.50) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL3476026 | 0.87 | MAPT (0.64) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL3476548 | 0.85 | MAPT (0.46) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL2772967 | 0.84 | KMT2A (0.46) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL2772066 | 0.84 | MAPT (0.49) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL3475816 | 0.84 | HRH4 (0.46) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL3478434 | 0.83 | GAA (0.53) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL2772271 | 0.81 | ALDH1A1 (0.46) | MAPTKMT2AMEN1GAALMNA | |
| SCHEMBL2773057 | 0.80 | KMT2A (0.53) | MAPTKMT2AMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | claimed |
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | disclosed |