SCHEMBL3476992

SCHEMBL3476992

Cn1ccc2cc(-c3ccc4oc(Nc5ccccc5)nc4c3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478143 0.90 FAAH (0.81) FAAH
SCHEMBL13436722 0.89 FAAH (0.80) FAAH
SCHEMBL3477039 0.89 FAAH (1.00) FAAH
SCHEMBL13436716 0.88 FAAH (1.00) FAAH
SCHEMBL3478529 0.87 FAAH (1.00) FAAH
SCHEMBL3477560 0.86 FAAH (0.79) FAAH
SCHEMBL3477451 0.85 FAAH (1.00) FAAH
SCHEMBL3478203 0.84 FAAH (1.00) FAAH
SCHEMBL3478456 0.84 FAAH (0.72) FAAH
SCHEMBL3477803 0.83 FAAH (0.76) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed