Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478425 | 0.95 | FAAH (0.57) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3478220 | 0.90 | CYP1A2 (0.57) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3477459 | 0.80 | FAAH (0.57) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL13436718 | 0.79 | FAAH (0.57) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3477906 | 0.79 | FAAH (0.55) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL13436702 | 0.77 | FAAH (0.61) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3475856 | 0.77 | FAAH (0.65) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3474216 | 0.77 | FAAH (0.62) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3476446 | 0.77 | FAAH (0.61) | FAAHALDH1A1NPC1GAARAB9A | |
| SCHEMBL3475208 | 0.77 | FAAH (0.61) | FAAHALDH1A1NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |