Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889676 | 0.84 | NPC1 (0.47) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL1298878 | 0.84 | NPC1 (0.52) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL2388875 | 0.83 | MEN1 (0.44) | ARMAPTPOLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9245391 | 0.82 | AR (0.42) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL1842078 | 0.81 | NPC1 (0.47) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL7258024 | 0.81 | NPC1 (0.44) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL20644785 | 0.81 | AR (0.46) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL9323836 | 0.81 | AR (0.56) | ARMAPTRAB9AHTT | |
| SCHEMBL26106290 | 0.81 | NPC1 (0.44) | ARNPC1MAPTNOD2NOD1 | |
| SCHEMBL14099809 | 0.81 | NPC1 (0.44) | ARNPC1MAPTNOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113439084-B | Sesqui-carcinomycin analogue | 奥克兰联合服务有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | US | disclosed |
| EP-3917933-A1 | DUOCARMYCIN ANALOGUES | Auckland Uniservices Limited (NZ) | 2021-12-08 | — | — | EP | disclosed |
| CN-113439084-A | Duocarmycin analogs | 奥克兰联合服务有限公司 | 2021-09-24 | — | — | CN | disclosed |
| WO-2020157662-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-08-06 | — | — | WO | disclosed |
| EP-1910330-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED THIAZOLES, PYRROLES AND THIOPHENES | AICURIS GMBH & CO KG (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-8410090-B2 | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | AICURIS GMBH & CO. KG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8410090-B2 | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | AICURIS GMBH & CO. KG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8410090-B2 | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | AICURIS GMBH & CO. KG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20100144752-A1 | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | US | disclosed |
| US-5534483-A | (2-imidazolin-2-yl) fused heteropyridine compounds intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5534485-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5534484-A | (2-imidazolin-2-yl)fused heteropyridine compounds intermediates for the preparation of and use of said compounds and herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5532207-A | CONTROL OF MONO- AND DI-COTYLEDONOUS ANNUAL, PERENNIAL AND AQUATIC PLANTS; PRE- AND POST-EMERGENCE USE | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| US-5510319-A | PYRROLO-2,3-B-PYRIDINYL DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5252538-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0227932-B1 | NOVEL FUSED PYRIDINE COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0227932-A1 | Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4382143-A | Hypolipidemic and antiatherosclerotic novel (monosubstituted-amino)heteroaryl carboxylic acids and analogs | AMERICAN CYANAMID COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144752-A1 | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | TPMT, TYMP, TYMS | AR 4786/4885NPC1 2482/4885MAPT 1241/4885 |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | TOP2A, TOP2B, MUS81 | AR 4235/4885NPC1 3762/4885MAPT 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.