Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 16/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475560 | 0.78 | HRH4 (0.62) | HRH4 | |
| SCHEMBL3475562 | 0.75 | HRH4 (0.57) | HRH4 | |
| SCHEMBL3475980 | 0.75 | HRH4 (0.56) | HRH4 | |
| SCHEMBL3477674 | 0.74 | HRH4 (0.69) | HRH4 | |
| SCHEMBL2908130 | 0.72 | HRH4 (0.79) | HRH4 | |
| SCHEMBL3477162 | 0.72 | HRH4 (0.61) | HRH4SSTR5KCNH2 | |
| SCHEMBL3477289 | 0.70 | HRH4 (0.45) | HRH4SSTR5KCNH2 | |
| SCHEMBL3476597 | 0.69 | HRH4 (0.67) | HRH4 | |
| SCHEMBL605400 | 0.69 | HRH4 (0.58) | HRH4 | |
| SCHEMBL3477164 | 0.69 | HRH4 (0.55) | HRH4SSTR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004188-B1 | BENZOIMIDAZOL-2-YL PYRIDINES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-01 | — | — | EP | disclosed |